Genesis partnered with the National Institute for Communicable Diseases (NICD) on a landmark household cohort study in South Africa, central to the country’s efforts to monitor vaccine-preventable illnesses and shape national immunisation policy. From 2022 to 2025, Genesis led the SARS-CoV-2 and Multi-pathogen Serosurveillance (SAMS) longitudinal study, bringing deep expertise in data collection, management, and quality assurance to a complex, multi-year research programme.

For too long, crucial decisions about early childhood development (ECD) in South Africa lacked authoritative data, limiting effective policy-making and strategic investment. The Thrive by Five (TB5) Index, launched in 2021, emerged to fill this critical gap. Now the largest nationally representative survey of preschool child development in South Africa, the Index has directly informed government strategies, including the National Planning Commission’s 2024 2024 ECD Advisory Document and the Department of Basic Education’s 2030 Strategy for ECD Programmes.